The San Francisco Regional Financial Center (RFC) is one of four Treasury Financial Management Service processing centers. The San Francisco RFC employs about 114 people. The other three RFCs are located in Austin, TX, Kansas City, MO, and Philadelphia, PA.

RFCs disburse payments (either electronic funds transfers (EFT) or check) on behalf of virtually every federal agency in the Executive Branch except for the Department of Defense and certain independent agencies, such as the U.S. Postal Service. In fact, FMS disburses approximately 85 percent of all federal payments.

The work at the RFCs has evolved from disbursing handwritten checks to disbursing payments by EFT and printing paper checks using high-speed check printers. Since February 2001, the San Francisco RFC has been printing paper checks on high-speed laser printers that can print more than 60,000 checks per hour, compared with the 12,000 check-per-hour printing capabilities of its impact printers.